Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698203 | 0.71 | L3MBTL1 (0.44) | RAB9ANAMPTL3MBTL1CYP17A1CTSL | |
| SCHEMBL27353303 | 0.70 | CTSL (0.37) | CTSLCTSBGPR119 | |
| SCHEMBL2371450 | 0.69 | CTSL (0.34) | RAB9ANAMPTL3MBTL1CYP17A1CTSL | |
| SCHEMBL28162958 | 0.69 | IDO1 (0.38) | RAB9ANAMPTL3MBTL1CYP17A1CTSL | |
| SCHEMBL28696225 | 0.68 | RAB9A (0.40) | RAB9ANAMPTL3MBTL1CYP17A1CTSL | |
| SCHEMBL15507032 | 0.68 | ABCB1 (0.36) | CYP17A1ATR | |
| SCHEMBL2689360 | 0.67 | HTT (0.44) | RAB9ANAMPTCYP3A4HTTGPR119 | |
| SCHEMBL23878447 | 0.67 | PCSK9 (0.35) | L3MBTL1CYP17A1CTSLNFKB1NFKB2 | |
| SCHEMBL9923086 | 0.67 | RAB9A (0.36) | RAB9AHTT | |
| SCHEMBL29041112 | 0.66 | RAB9A (0.37) | RAB9ANAMPTL3MBTL1CYP17A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111155-B | A kind of synthetic method of 4,7- diaza spiro [2.5] octane -7- t-butyl formate | 武汉工程大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-105111155-A | Synthesis method of tert-butyl 4,7-diazaspiro[2.5]octyl-7-formate | WUHAN INST TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |