Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177528 | 0.83 | SRD5A2 (0.53) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL448815 | 0.79 | RARB (0.50) | SRD5A2RARBMEN1CYP1A2KMT2A | |
| SCHEMBL9653084 | 0.79 | SRD5A2 (0.57) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL444583 | 0.79 | MEN1 (0.59) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL11772204 | 0.78 | SRD5A2 (0.65) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL3487445 | 0.77 | RARB (0.47) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL5486023 | 0.77 | TP53 (0.53) | SRD5A2RARBMEN1KMT2ATP53 | |
| SCHEMBL448814 | 0.77 | SHBG (0.59) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL2804705 | 0.77 | SRD5A2 (0.55) | SRD5A2RARBRARGMEN1CYP1A2 | |
| SCHEMBL3528575 | 0.77 | TAAR1 (0.57) | SRD5A2RARBRARGMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816364-B1 | Reagents for lysergic acid diethylamide immunoassay | HOFFMANN LA ROCHE (CH) | 2004-01-02 | — | — | EP | disclosed |
| US-6476199-B1 | Reagents for lysergic acid diethylamide immunoassay | ROCHE DIAGNOSTICS CORPORATION | 2002-11-05 | — | — | US | disclosed |
| US-6063908-A | STABLE HAPTEN DERIVATIVES THAT ARE USEFUL FOR THE PREPARATION OF ANTIGENS, ANTIBODIES AND REAGENTS USED IN DETECTION OF DRUG ABUSE | ROCHE DIAGNOSTICS CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0816364-A1 | Reagents for lysergic acid diethylamide immunoassay | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |