Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047359 | 0.94 | KMT2A (0.65) | DPP4KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28010257 | 0.87 | KMT2A (0.57) | DPP4KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL555383 | 0.84 | DPP4 (0.61) | DPP4KMT2AALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL28047367 | 0.84 | DPP4 (0.54) | DPP4KMT2APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28010961 | 0.83 | KMT2A (0.52) | KMT2APOLBALDH1A1HSD17B10TP53 | |
| SCHEMBL28047331 | 0.83 | KMT2A (0.65) | DPP4KMT2APOLBALDH1A1ALOX15 | |
| SCHEMBL5470935 | 0.79 | DPP4 (0.57) | DPP4KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL1242754 | 0.79 | ALDH1A1 (0.60) | DPP4KMT2AALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5638863 | 0.79 | DPP4 (0.74) | DPP4KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28047358 | 0.78 | KMT2A (0.58) | DPP4KMT2APOLBALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373999-B | purine compound, intermediate, preparation method and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-01-13 | — | — | CN | disclosed |