Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047358 | 0.94 | KMT2A (0.58) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL28010287 | 0.89 | KMT2A (0.52) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL28047362 | 0.84 | DPP4 (0.59) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL555383 | 0.79 | DPP4 (0.61) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL28047331 | 0.78 | KMT2A (0.65) | DPP4KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28047359 | 0.78 | KMT2A (0.65) | DPP4KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1242754 | 0.76 | ALDH1A1 (0.60) | DPP4KMT2AALDH1A1TSHRTP53 | |
| SCHEMBL5638863 | 0.74 | DPP4 (0.74) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL5470935 | 0.74 | DPP4 (0.57) | DPP4KMT2AALDH1A1TSHRNPSR1 | |
| SCHEMBL28010257 | 0.72 | KMT2A (0.57) | DPP4KMT2AALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373999-B | purine compound, intermediate, preparation method and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-01-13 | — | — | CN | disclosed |