Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.59 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634388 | 0.81 | KMT2A (0.59) | TGM2TEAD4MAPK1KMT2AALDH1A1 | |
| SCHEMBL11143174 | 0.79 | TGM2 (0.66) | TGM2TEAD4MAPK1GSTO1KMT2A | |
| SCHEMBL1424434 | 0.78 | TGM2 (0.64) | TGM2TEAD4MAPK1GSTO1KMT2A | |
| SCHEMBL94878 | 0.76 | TGM2 (0.68) | TGM2TEAD4MAPK1GSTO1KMT2A | |
| SCHEMBL1530299 | 0.76 | TGM2 (0.49) | TGM2TEAD4GSTO1POLBF13A1 | |
| Acrylic Acid SCHEMBL28690059 | 0.76 | TGM2 (0.55) | TGM2ALDH1A1POLBF13A1LMNA | |
| SCHEMBL11335118 | 0.76 | TGM2 (0.61) | TGM2TEAD4MAPK1GSTO1KMT2A | |
| SCHEMBL19329702 | 0.75 | KEAP1 (0.59) | ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL10778839 | 0.74 | SMN1; SMN2 (0.52) | KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11348254 | 0.74 | TGM2 (0.59) | TGM2TEAD4MAPK1GSTO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746239-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBVIE INC. (BS) | 2016-02-10 | — | — | CN | disclosed |