Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 7/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784974 | 0.79 | DPP4 (0.43) | RORC | |
| SCHEMBL1596056 | 0.78 | KMT2A (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL30579808 | 0.76 | CYP2A6 (0.46) | ACLYMETAP2MEN1KMT2AGRM2 | |
| SCHEMBL27704448 | 0.76 | FABP4 (0.42) | ACLYPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28633398 | 0.75 | PRKAB2 (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL21250750 | 0.75 | NOTUM (0.40) | AKR1C2AKR1C1FABP3FABP4RORC | |
| SCHEMBL2136910 | 0.74 | CYP2A6 (0.56) | MEN1KMT2ACYP2A6FABP3FABP4 | |
| SCHEMBL31212990 | 0.74 | CYP2A6 (0.56) | MEN1KMT2ACYP2A6FABP3FABP4 | |
| SCHEMBL5787358 | 0.74 | AKR1C2 (0.61) | ACLYAKR1C2AKR1C1FABP3FABP4 | |
| SCHEMBL16460187 | 0.74 | RORC (0.43) | ACLYRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555761-A | Novel biphenyl derivatives and process for preparing the same | DONG A ST CO LTD | 2016-05-04 | — | — | CN | disclosed |