Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047685 | 0.94 | CA12 (0.44) | CA12CA1CA2CA9FFAR1 | |
| SCHEMBL28047836 | 0.78 | FFAR1 (0.53) | FFAR1FBP1MEN1CYP3A4PTGS1 | |
| SCHEMBL28047758 | 0.72 | FFAR1 (0.54) | FFAR1MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL28047693 | 0.70 | GRM2 (0.38) | FFAR1 | |
| SCHEMBL28515659 | 0.69 | CA12 (0.55) | CA12CA1CA2CA9TP53 | |
| SCHEMBL28047696 | 0.65 | FFAR1 (0.57) | FFAR1GAAMEN1CYP3A4KMT2A | |
| SCHEMBL28047856 | 0.64 | FFAR1 (0.56) | FFAR1FBP1MEN1CYP3A4PTGS1 | |
| SCHEMBL28520989 | 0.63 | CA12 (0.67) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6276169 | 0.63 | FFAR1 (0.71) | FFAR1FBP1MEN1CYP3A4PTGS1 | |
| SCHEMBL28527473 | 0.62 | CA12 (0.56) | CA12CA1CA2CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |