Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047696 | 0.84 | FFAR1 (0.57) | FFAR1CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28047836 | 0.84 | FFAR1 (0.53) | FFAR1NR1H2NR1H3CYP3A4MEN1 | |
| SCHEMBL28047856 | 0.83 | FFAR1 (0.56) | FFAR1NR1H2NR1H3CYP3A4MEN1 | |
| SCHEMBL6276169 | 0.82 | FFAR1 (0.71) | FFAR1CYP3A4MEN1PTGS1DRD3 | |
| Hydrochloric Acid SCHEMBL28047769 | 0.77 | ADRB2 (0.49) | — | |
| SCHEMBL28047852 | 0.75 | FFAR1 (0.50) | FFAR1CYP3A4 | |
| SCHEMBL28047685 | 0.75 | CA12 (0.44) | FFAR1 | |
| SCHEMBL28047701 | 0.74 | CYP3A4 (0.61) | FFAR1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL17106235 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2ATDP1 | |
| SCHEMBL28047801 | 0.72 | FFAR1 (0.62) | FFAR1CYP3A4SLC5A1SLC5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |