Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047758 | 0.84 | FFAR1 (0.54) | FFAR1MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL28047696 | 0.83 | FFAR1 (0.57) | FFAR1MEN1CYP3A4KMT2A | |
| SCHEMBL28047856 | 0.82 | FFAR1 (0.56) | FFAR1MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL6276169 | 0.81 | FFAR1 (0.71) | FFAR1MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL28047701 | 0.73 | CYP3A4 (0.61) | FFAR1CYP3A4KMT2A | |
| SCHEMBL28047801 | 0.71 | FFAR1 (0.62) | FFAR1CYP3A4 | |
| SCHEMBL28860997 | 0.71 | ALOX15 (0.42) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL31580496 | 0.70 | FFAR1 (1.00) | FFAR1BCL2L1FBP1 | |
| SCHEMBL3834439 | 0.69 | MAOB (0.52) | MEN1KMT2AALOX15 | |
| SCHEMBL28169742 | 0.69 | ALOX15 (0.50) | MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |