Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047701 | 0.89 | CYP3A4 (0.61) | FFAR1MAPTKMT2ACYP3A4CYP2D6 | |
| SCHEMBL28047856 | 0.86 | FFAR1 (0.56) | FFAR1MEN1KMT2ACYP3A4 | |
| SCHEMBL28047758 | 0.84 | FFAR1 (0.54) | FFAR1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL6276169 | 0.84 | FFAR1 (0.71) | FFAR1MEN1KMT2AHPGDCYP3A4 | |
| SCHEMBL28047836 | 0.83 | FFAR1 (0.53) | FFAR1MEN1KMT2ACYP3A4 | |
| SCHEMBL28968235 | 0.82 | MAPT (0.51) | SYNJ2MEN1MAPTKMT2AGAA | |
| SCHEMBL28047801 | 0.81 | FFAR1 (0.62) | FFAR1MAPTHPGDCYP3A4CYP2D6 | |
| SCHEMBL9119401 | 0.80 | SYNJ2 (0.54) | SYNJ2MEN1MAPTKMT2AGAA | |
| Aspidinol C SCHEMBL29761934 | 0.78 | FASN (0.67) | FFAR1MEN1KMT2ACYP3A4 | |
| SCHEMBL29664009 | 0.76 | CYP3A4 (0.61) | FFAR1MEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |