Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SDCBP | O00560 | 1/20 | 0.35 |
| ▸ | SDC2 | P34741 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047824 | 0.83 | CD274 (0.41) | TYR | |
| SCHEMBL11374972 | 0.71 | MAPK1 (0.39) | ITGB3ITGB1ITGAVITGA5ALDH1A1 | |
| SCHEMBL8349459 | 0.70 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5ALDH1A1 | |
| SCHEMBL8065362 | 0.70 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5ALDH1A1 | |
| SCHEMBL29060375 | 0.70 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28019583 | 0.69 | ALDH1A1 (0.60) | ITGB3ITGB1ITGAVITGA5ALDH1A1 | |
| SCHEMBL14520629 | 0.68 | ITGB3 (0.52) | ITGB3ITGB1ITGAVITGA5ADAMTS4 | |
| SCHEMBL12572489 | 0.68 | ITGB3 (0.52) | ITGB3ITGB1ITGAVITGA5ADAMTS4 | |
| SCHEMBL4622349 | 0.67 | SMN1; SMN2 (0.46) | ALDH1A1MAPK1 | |
| SCHEMBL29664208 | 0.67 | ITGB1 (0.71) | ITGB3ITGB1ITGAVITGA5ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | claimed |
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |