Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 5/20 | 0.43 |
| ▸ | NOS2 | P35228 | 5/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720436 | 0.75 | POLB (0.42) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL2380248 | 0.75 | MAPT (0.41) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL5861792 | 0.75 | UHRF1 (0.46) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL2531556 | 0.75 | NOTUM (0.47) | MAPTNOS3NOS2NOS1KDM4E | |
| SCHEMBL14858374 | 0.74 | NOS3 (0.46) | NOS3NOS2NOS1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL14858743 | 0.73 | NOTUM (0.46) | MAPTNOS3NOS2NOS1KDM4E | |
| SCHEMBL26077742 | 0.72 | NOS3 (0.39) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL20241939 | 0.72 | ELOVL1 (0.43) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL10175045 | 0.72 | CYP2E1 (0.50) | NOS3NOS2NOS1KDM4EMEN1 | |
| SCHEMBL17768008 | 0.71 | NOTUM (0.51) | NOS3NOS2NOS1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315283-A | Bruton tyrosine kinases inhibitor | CHENGDU BEISIKAIRUI BIOTECHNOLOGY CO LTD | 2016-02-10 | — | — | CN | disclosed |