Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102570 | 0.79 | HTR2A (0.50) | MAOB | |
| SCHEMBL20916278 | 0.78 | CYP3A4 (0.39) | RAB9A | |
| SCHEMBL29454253 | 0.76 | TAAR1 (0.45) | TAAR1MPOIDO1AGXTMAOB | |
| SCHEMBL22232600 | 0.76 | TAAR1 (0.45) | TAAR1MPOIDO1AGXTMAOB | |
| SCHEMBL3300303 | 0.76 | TAAR1 (0.60) | TAAR1IDO1AGXTMAOBDAO | |
| SCHEMBL3132841 | 0.76 | CD44 (0.46) | L3MBTL1 | |
| SCHEMBL6694964 | 0.76 | MPO (0.42) | TAAR1MPOIDO1AGXTMAOB | |
| SCHEMBL2091696 | 0.76 | TAAR1 (0.52) | TAAR1MPOIDO1AGXTL3MBTL1 | |
| SCHEMBL7205931 | 0.76 | TAAR1 (0.52) | TAAR1MPOIDO1AGXTMAOB | |
| SCHEMBL4221500 | 0.75 | TAAR1 (0.56) | TAAR1MPOIDO1AGXTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189481-A | Pyridine cdk9 kinase inhibitors | ABBVIE INC | 2015-12-23 | — | — | CN | disclosed |