Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037241 | 0.82 | TAAR1 (0.50) | TAAR1IDO1AGXTMAOBMIF | |
| SCHEMBL3300303 | 0.80 | TAAR1 (0.60) | TAAR1IDO1AGXTMAOBMIF | |
| SCHEMBL16113498 | 0.78 | GAA (0.45) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL6694964 | 0.77 | MPO (0.42) | TAAR1IDO1AGXTMAOBMPO | |
| SCHEMBL29442846 | 0.76 | MAOB (0.59) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL21384149 | 0.76 | MAOB (0.59) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL28047780 | 0.76 | TAAR1 (0.47) | TAAR1IDO1AGXTMAOBMIF | |
| SCHEMBL28036818 | 0.74 | TAAR1 (0.60) | TAAR1IDO1AGXTMAOBMIF | |
| SCHEMBL3298408 | 0.74 | CALM1 (0.57) | TAAR1IDO1AGXTMIFDAO | |
| SCHEMBL1498780 | 0.73 | CALM1 (0.55) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |