Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047859 | 0.87 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL28321480 | 0.84 | CYP3A4 (0.50) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL656327 | 0.81 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30792317 | 0.81 | CYP3A4 (0.58) | CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28047701 | 0.80 | CYP3A4 (0.61) | FFAR1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9578154 | 0.76 | NFKB1 (0.61) | FFAR1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30792196 | 0.76 | ABCG2 (0.41) | CYP3A4 | |
| SCHEMBL28047801 | 0.76 | FFAR1 (0.62) | FFAR1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28047758 | 0.75 | FFAR1 (0.54) | FFAR1CYP3A4 | |
| SCHEMBL28047696 | 0.75 | FFAR1 (0.57) | FFAR1CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189446-A | Phloroglucinol derivatives and application thereof in treatment of neurodegenerative disorder | INST MATERIA MEDICA CAMS | 2015-12-23 | — | — | CN | disclosed |