SCHEMBL28047880

SCHEMBL28047880

CC(=NO)c1ccccc1.CCc1ccc(O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TP53 P04637 1/20 0.43
ESR1 P03372 5/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
MAPK1 P28482 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 2/20 0.42
CYP19A1 P11511 2/20 0.42
ESR2 Q92731 2/20 0.42
APAF1 O14727 1/20 0.42
USP2 O75604 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19938067 0.83 ALDH1A1 (0.50) MEN1KMT2AMAPK1ALDH1A1GAA
SCHEMBL7873597 0.83 ALDH1A1 (0.50) MEN1KMT2AMAPK1ALDH1A1GAA
SCHEMBL28741400 0.79 ALDH1A1 (0.52) MEN1KMT2ATP53ESR1L3MBTL1
Phenol SCHEMBL7656573 0.79 TP53 (0.62) MEN1KMT2ATP53ESR1L3MBTL1
Ethylbenzene SCHEMBL27772548 0.79 TP53 (0.70) MEN1KMT2ATP53ESR1L3MBTL1
SCHEMBL2736631 0.79 LMNA (0.52) L3MBTL1MAPK1ALDH1A1HSD17B10GAA
SCHEMBL45278 0.79 LMNA (0.52) L3MBTL1MAPK1ALDH1A1HSD17B10GAA
SCHEMBL257242 0.79 LMNA (0.52) L3MBTL1MAPK1ALDH1A1HSD17B10GAA
Benzene SCHEMBL28280701 0.79 LMNA (0.52) L3MBTL1MAPK1ALDH1A1HSD17B10GAA
SCHEMBL11266105 0.77 LMNA (0.50) L3MBTL1MAPK1ALDH1A1HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103920530-B The preparation method of 2-hydroxyl-5-alkylacetophenone oxime and used catalyst SICHUAN ZHIJIANG ADVANCED MATERIALS CO., LTD. (CN) 2015-12-09 CN claimed
CN-103920530-B The preparation method of 2-hydroxyl-5-alkylacetophenone oxime and used catalyst SICHUAN ZHIJIANG ADVANCED MATERIALS CO., LTD. (CN) 2015-12-09 CN disclosed