Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 6/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371995 | 0.79 | SCN2A (0.61) | SCN2ANPY5RPIN1HPGDSRECQL | |
| SCHEMBL11515707 | 0.78 | SCN2A (0.64) | SCN2ANPY5RHPGDS | |
| SCHEMBL12498267 | 0.76 | SMPD3 (0.45) | SCN2ANPY5RPIN1HPGDSRECQL | |
| SCHEMBL27817123 | 0.72 | SCN2A (0.79) | SCN2ANPY5RHPGDS | |
| SCHEMBL12499046 | 0.72 | DGAT1 (0.46) | SCN2A | |
| SCHEMBL11634539 | 0.69 | NPC1 (0.38) | — | |
| SCHEMBL28047903 | 0.68 | PIN1 (0.32) | SCN2ANPY5RPIN1 | |
| SCHEMBL27836624 | 0.66 | SCN2A (0.52) | SCN2ANPY5RHPGDS | |
| SCHEMBL926141 | 0.66 | MAPT (0.47) | — | |
| SCHEMBL4585526 | 0.64 | NISCH (0.36) | SCN2ANPY5RHPGDSRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189506-A | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG | 2015-12-23 | — | — | CN | disclosed |