Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL9443134 | 0.95 | GPR35 (0.63) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Dinitro Cresol SCHEMBL1509581 | 0.92 | GPR35 (0.78) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL31588165 | 0.88 | GPR35 (0.71) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL9443183 | 0.88 | GPR35 (0.71) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL31588669 | 0.87 | GPR35 (0.73) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL27955220 | 0.86 | CRHBP (0.79) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL27538937 | 0.86 | CRHBP (0.62) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Toluene SCHEMBL28998637 | 0.84 | GPR35 (0.73) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL28287535 | 0.84 | GPR35 (0.63) | GPR35ALDH1A1CRHBPCRHR2MAPT | |
| Trinitrophenol SCHEMBL29086892 | 0.83 | GPR35 (0.74) | GPR35ALDH1A1CRHBPCRHR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025859-A | Formula of ferrous picrate fuel additive | 中勘天府科技(四川)有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-109406740-A | A kind of evaluation method of freshwater fish quality | 湖北省农业科学院农产品加工与核农技术研究所 | 2019-03-01 | — | — | CN | claimed |
| CN-120025859-A | Formula of ferrous picrate fuel additive | 中勘天府科技(四川)有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-118318970-A | Meat-based prepared vegetable flavoring agent and preparation method thereof | 山东凯欣绿色食品股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117958307-A | Algae deodorization device and deodorization method based on tea polyphenol | 福建农林大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-115104695-B | Method for removing fishy smell of crucian | 黄冈师范学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-115104695-A | Method for removing fish smell of crucian | 黄冈师范学院 | 2022-09-27 | — | — | CN | disclosed |
| CN-108419981-B | Yellow croaker fishy smell removing agent and preparation and use methods thereof | 浙江万里学院 | 2021-07-16 | — | — | CN | disclosed |
| CN-112029818-A | Method for screening trimethylamine lyase inhibitor by using microorganisms | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |
| CN-109406740-A | A kind of evaluation method of freshwater fish quality | 湖北省农业科学院农产品加工与核农技术研究所 | 2019-03-01 | — | — | CN | disclosed |
| CN-108419981-A | Yellow croaker fishy smell removing agent and preparation and use methods thereof | 浙江万里学院 | 2018-08-21 | — | — | CN | disclosed |
| CN-105136968-B | A kind of supramolecular organogel compositions and application thereof | 中北大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105136968-A | Super-molecular organic gel composition and application thereof | UNIV NORTH CHINA | 2015-12-09 | — | — | CN | disclosed |