Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL28048084 | 0.92 | GPR35 (0.64) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL1716451 | 0.92 | GPR35 (0.93) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Trinitrophenol SCHEMBL9443134 | 0.91 | GPR35 (0.63) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL3976321 | 0.91 | GPR35 (0.78) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL892354 | 0.91 | ALDH1A1 (0.78) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL2549698 | 0.90 | GPR35 (0.89) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL6859521 | 0.90 | GPR35 (0.96) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL9221013 | 0.89 | ALDH1A1 (0.81) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL4735684 | 0.89 | GPR35 (0.81) | GPR35ALDH1A1MAPTHPGDKDM4E | |
| Dinitro Cresol SCHEMBL20734 | 0.88 | GPR35 (1.00) | GPR35ALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10859317-B2 | Apparatus and method for evaporating liquids containing potentially explosive impurities | COVESTRO DEUTSCHLAND AG (DE) | 2020-12-08 | — | — | US | claimed |
| EP-3180578-B1 | APPARATUS AND METHOD FOR EVAPORATING LIQUIDS CONTAINING POTENTIALLY EXPLOSIVE IMPURITIES | COVESTRO DEUTSCHLAND AG (DE) | 2019-11-06 | — | — | EP | claimed |
| CN-109718779-A | A kind of ball-type skeleton Ni hydrogenation catalyst and its preparation method and application | 万华化学集团股份有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-108997137-A | The method for preparing toluenediamine by catalytic hydrogenation dinitrotoluene (DNT) | 麻城市天恒商贸有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-107899581-A | One kind is carried on SiO2The preparation method and applications of Raney nickel on microballoon | 万华化学集团股份有限公司 | 2018-04-13 | — | — | CN | claimed |
| CN-107570147-A | A kind of application process of active metal/metal packing catalyst in hydrogenation of dinitro toluene synthesis toluenediamine reaction | 河北工业大学 | 2018-01-12 | — | — | CN | claimed |
| CN-107325006-A | A kind of technique of hydrogenation of dinitro toluene tubular type thickening | 赛鼎工程有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-107233887-A | A kind of preparation method and application of the catalyst of hydrogenation of dinitro toluene synthesis toluencediamine | 太原理工大学 | 2017-10-10 | — | — | CN | claimed |
| US-20170227294-A1 | APPARATUS AND METHOD FOR EVAPORATING LIQUIDS CONTAINING POTENTIALLY EXPLOSIVE IMPURITIES | COVESTRO DEUTSCHLAND AG (DE) | 2017-08-10 | — | — | US | claimed |
| EP-3180578-A1 | APPARATUS AND METHOD FOR EVAPORATING LIQUIDS CONTAINING POTENTIALLY EXPLOSIVE IMPURITIES | Covestro Deutschland AG (DE) | 2017-06-21 | — | — | EP | claimed |
| WO-2004033048-A1 | DECOMPOSITION OF NITROGEN-BASED ENERGETIC MATERIAL | KORNEL ALFRED (US) | 2004-04-22 | — | — | WO | claimed |
| EP-0876335-B2 | PRODUCTION OF ISOCYANATE USING CHLORINE RECYCLE | UNIV SOUTH CAROLINA RES FOUND (US) | 2004-03-31 | — | — | EP | claimed |
| US-6254789-B1 | Method for treating aqueous solutions comprising acids and nitrated compounds | RHODIA CHIMIE (FR) | 2001-07-03 | — | — | US | claimed |
| EP-0876335-B1 | PRODUCTION OF ISOCYANATE USING CHLORINE RECYCLE | DU PONT (US) | 2000-05-10 | — | — | EP | claimed |
| CN-1245163-A | Application of whole catalyst for producing tolylene diamine by hydrogenation of dinitro toluene | AIR PROD & CHEM (US) | 2000-02-23 | — | — | CN | claimed |
| EP-0876335-A1 | PRODUCTION OF ISOCYANATE USING CHLORINE RECYCLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997024320-A1 | PRODUCTION OF ISOCYANATE USING CHLORINE RECYCLE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-10 | — | — | WO | claimed |
| EP-0660818-A1 | A PROCESS FOR PREPARING DINITROTOLUENE | OLIN CORPORATION (US) | 1995-07-05 | — | — | EP | claimed |
| EP-0660818-A4 | A PROCESS FOR PREPARING DINITROTOLUENE. | OLIN CORP (US) | 1995-05-23 | — | — | EP | claimed |
| WO-1994006751-A1 | A PROCESS FOR PREPARING DINITROTOLUENE | OLIN CORPORATION (US) | 1994-03-31 | — | — | WO | claimed |