Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700554 | 0.88 | HCAR2 (0.39) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| SCHEMBL16491297 | 0.76 | CYP11B2 (0.41) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| Formic Acid SCHEMBL27869530 | 0.75 | HCAR2 (0.44) | HCAR2MKNK1MKNK2CHRNB2CHRNA4 | |
| SCHEMBL22585762 | 0.73 | HCAR2 (0.38) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| SCHEMBL8447350 | 0.73 | HCAR2 (0.38) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| SCHEMBL28468744 | 0.72 | ADRB2 (0.46) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| SCHEMBL20775371 | 0.72 | ADRB2 (0.46) | HCAR2ADORA2BADORA1MKNK1MKNK2 | |
| SCHEMBL17000186 | 0.72 | HCAR2 (0.36) | HCAR2ADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL725480 | 0.72 | PRMT5 (0.34) | — | |
| SCHEMBL1920603 | 0.72 | HCAR2 (0.37) | HCAR2MKNK1MKNK2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164121-A | Perfluorinated cyclopropyl-fused 1, 3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use thereof | AMGEN INC | 2015-12-16 | — | — | CN | disclosed |