Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209293 | 0.86 | MAPT (0.47) | MAPTLMNAPOLBGAAMRGPRX4 | |
| SCHEMBL2506125 | 0.81 | LMNA (0.52) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2479165 | 0.77 | MAPT (0.45) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL8205428 | 0.76 | PKM (0.47) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2502362 | 0.76 | LMNA (0.47) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2479074 | 0.76 | MAPT (0.47) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2517937 | 0.75 | KMT2A (0.49) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2506210 | 0.75 | MAPT (0.46) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2480016 | 0.74 | MAPT (0.43) | MAPTLMNAPOLBGAAKMT2A | |
| SCHEMBL2479343 | 0.74 | MAPT (0.43) | MAPTLMNAPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104030908-B | The preparation method of chloro-10,11-dihydro-5H-dibenzo [a, the d] suberene-5-ketone of a kind of 2,4-bis- | CHIEN-SHIUNG INSTITUTE OF TECHNOLOGY (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-104030908-B | The preparation method of chloro-10,11-dihydro-5H-dibenzo [a, the d] suberene-5-ketone of a kind of 2,4-bis- | CHIEN-SHIUNG INSTITUTE OF TECHNOLOGY (CN) | 2016-01-20 | — | — | CN | disclosed |