SCHEMBL8209293

SCHEMBL8209293

O=C(Oc1c(Cl)cc(Cl)cc1Cl)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 2/20 0.47
F2 P00734 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
PARP10 Q53GL7 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
CA12 O43570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28048273 0.86 MAPT (0.45) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL8205428 0.86 PKM (0.47) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL9161406 0.85 LMNA (0.50) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL9169328 0.83 KMT2A (0.42) MAPTKMT2AMEN1SMN1; SMN2NPC1
SCHEMBL2884565 0.82 LMNA (0.52) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL30586317 0.80 ALDH1A1 (0.56) MAPTKMT2AMEN1LMNANPC1
SCHEMBL11349562 0.80 CA1 (0.44) MAPTKMT2AMEN1LMNAF2
SCHEMBL5551848 0.80 LMNA (0.64) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL5787359 0.79 MAPT (0.58) MAPTKMT2AMEN1TDP1LMNA
SCHEMBL14590886 0.79 NPC1 (0.41) MAPTKMT2AMEN1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed