Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908217 | 0.88 | CCNB2 (0.53) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL28520349 | 0.86 | CCNB2 (0.45) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL28517696 | 0.81 | CCNE2 (0.42) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL27590753 | 0.79 | ALDH1A1 (0.40) | LMNAMAPTCYP3A4SLC6A3ALDH1A1 | |
| SCHEMBL533850 | 0.78 | CCNB2 (0.53) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL28022639 | 0.75 | ELANE (0.40) | LMNAMAPTMEN1SLC6A3KMT2A | |
| SCHEMBL10758904 | 0.74 | MAPT (0.48) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL295133 | 0.73 | CCNB2 (0.53) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL4479542 | 0.73 | LMNA (0.58) | CCNB2CCNE2CDK1CCNB1CCNE1 | |
| SCHEMBL5154293 | 0.73 | CCNB2 (0.53) | CCNB2CCNE2CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555816-A | Silicone hydrogel lenses with relatively long thermal stability | NOVARTIS AG | 2016-05-04 | — | — | CN | claimed |
| CN-105579480-B | Method for making UV absorbing ophthalmic lenses | 诺华股份有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-105579480-A | Method for making UV absorbing ophthalmic lenses | NOVARTIS AG | 2016-05-11 | — | — | CN | disclosed |