Sugi Predict

Sugi Predict / Compounds / SCHEMBL533850

SCHEMBL533850

SCHEMBL533850

CCCCCCCCCCCCCCCCCCOc1ccc(C(=O)c2ccccc2)c(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCNB2 O95067 1/20 0.53
▸ CCNE2 O96020 1/20 0.53
▸ CDK1 P06493 1/20 0.53
▸ CCNB1 P14635 1/20 0.53
▸ CCNE1 P24864 1/20 0.53
▸ CDK2 P24941 1/20 0.53
▸ CCNB3 Q8WWL7 1/20 0.53
▸ PTPN11 Q06124 3/20 0.52
▸ CNR1 P21554 3/20 0.52
▸ CNR2 P34972 3/20 0.52
▸ LMNA P02545 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ NR1I2 O75469 1/20 0.51
▸ CHRM2 P08172 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ ADRA2A P08913 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ OPRK1 P41145 1/20 0.51
▸ HTR2B P41595 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163358 0.94 CNR1 (0.50) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL5829566 0.90 MAPT (0.51) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL4479542 0.89 LMNA (0.58) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL28330270 0.86 LMNA (0.55) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL15908217 0.86 CCNB2 (0.53) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL7850202 0.84 MAPT (0.61) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL27993046 0.84 MAPT (0.61) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL27995934 0.84 MAPT (0.61) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL13164712 0.84 CCNB2 (0.42) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL9898532 0.83 LMNA (0.52) CCNB2CCNE2CDK1CCNB1CCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3263579-B1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO KK (JP) 2022-11-30 — — EP disclosed
EP-4049991-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2022-08-31 — — EP disclosed
US-10464966-B2 Precipitation promoter and precipitation method in which same is used AJINOMOTO CO., INC. (JP) 2019-11-05 — — US disclosed
EP-2711370-B1 METHOD FOR PRODUCING OLIGONUCLEOTIDES AJINOMOTO KK (JP) 2018-01-03 — — EP disclosed
EP-3263579-A1 PRECIPITATION ACCELERATOR AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2018-01-03 — — EP disclosed
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2017-11-09 — — US disclosed
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED AJINOMOTO CO., INC. (JP) 2017-11-09 — — US disclosed
US-9670121-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2017-06-06 — — US disclosed
US-20160060198-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2016-03-03 — — US disclosed
US-9169187-B2 Method of making peptides using diphenylmethane compound AJINOMOTO CO., INC. (JP) 2015-10-27 — — US disclosed
US-9029528-B2 Solution-based method of making oligonucleotides via phosphoramidite coupling AJINOMOTO CO., INC. (JP) 2015-05-12 — — US disclosed
US-20140213761-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC (JP) 2014-07-31 — — US disclosed
US-8722934-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2014-05-13 — — US disclosed
US-8722934-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2014-05-13 — — US disclosed
EP-2711370-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-03-26 — — EP disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 — — US disclosed
EP-2415745-A1 DIPHENYLMETHANE COMPOUND Ajinomoto Co., Inc. (JP) 2012-02-08 — — EP disclosed
US-20100249374-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2010-09-30 — — US disclosed
US-20100249374-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2010-09-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249374-A1 DIPHENYLMETHANE COMPOUND CCKAR, DNPEP, QPCTL CCNB2 578/4885CCNE2 786/4885CDK1 609/4885
US-20140213761-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR CCNB2 755/4885CCNE2 894/4885CDK1 499/4885
US-20160060198-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR CCNB2 755/4885CCNE2 894/4885CDK1 499/4885
US-20170320904-A1 PRECIPITATION PROMOTER AND PRECIPITATION METHOD IN WHICH SAME IS USED SP1, MED25, CTCF CCNB2 1000/4885CCNE2 2143/4885CDK1 2750/4885
US-10464966-B2 Precipitation promoter and precipitation method in which same is used SP1, MED25, CTCF CCNB2 1000/4885CCNE2 2143/4885CDK1 2750/4885
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT CCNB2 4255/4885CCNE2 3902/4885CDK1 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.