Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL6112781 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL28318521 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL285675 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL6112776 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL345048 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL9449859 | 1.00 | CA2 (0.50) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL7565065 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL7775151 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL718179 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 | |
| Phosphoric Acid SCHEMBL4107570 | 0.95 | CA2 (0.46) | CA2CA1CA9BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108273129-A | A kind of compound calcium phosphate bone cement and the preparation method and application thereof of anti-collapsibility and high intensity | 暨南大学 | 2018-07-13 | — | — | CN | claimed |
| CN-105233334-B | A kind of calcium phosphate bone cement of anti-collapsibility and preparation method thereof, application | 华南理工大学 | 2018-05-15 | — | — | CN | claimed |
| CN-107233627-A | A kind of calcium phosphate bone cement containing konjaku glucomannan and its preparation method and application | 华南理工大学 | 2017-10-10 | — | — | CN | claimed |
| CN-105233334-A | Calcium phosphate bone cement with collapse resistance as well as preparation method and application thereof | UNIV SOUTH CHINA TECH | 2016-01-13 | — | — | CN | claimed |
| CN-108273129-A | A kind of compound calcium phosphate bone cement and the preparation method and application thereof of anti-collapsibility and high intensity | 暨南大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-105233334-B | A kind of calcium phosphate bone cement of anti-collapsibility and preparation method thereof, application | 华南理工大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-107233627-A | A kind of calcium phosphate bone cement containing konjaku glucomannan and its preparation method and application | 华南理工大学 | 2017-10-10 | — | — | CN | disclosed |
| CN-105233334-A | Calcium phosphate bone cement with collapse resistance as well as preparation method and application thereof | UNIV SOUTH CHINA TECH | 2016-01-13 | — | — | CN | disclosed |