Phosphoric Acid

Phosphoric Acid

SCHEMBL345048

O=C(O)O.O=P(O)(O)O.[CaH2]

nearest known ligand 0.54

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.50
CA1 P00915 1/20 0.50
CA9 Q16790 1/20 0.50
BLM P54132 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC34A1 Q06495 1/20 0.36
MMP2 P08253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PEPD P12955 1/20 0.33
FDPS P14324 1/20 0.33
CA4 P22748 2/20 0.32
MMP3 P08254 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL6112781 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL28048398 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL28318521 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL285675 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL6112776 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL9449859 1.00 CA2 (0.50) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL7565065 0.95 CA2 (0.46) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL7775151 0.95 CA2 (0.46) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL718179 0.95 CA2 (0.46) CA2CA1CA9BLMTDP1
Phosphoric Acid SCHEMBL4107570 0.95 CA2 (0.46) CA2CA1CA9BLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114931540-B Carboxymethyl bagasse-containing composite material and preparation method and application thereof 云南白药集团健康产品有限公司 2023-07-14 CN claimed
EP-3505597-B1 HALOGEN-FREE FIXED FLAME RETARDANT MIXTURE AND ITS USE CLARIANT INT LTD (CH) 2022-08-31 EP claimed
CN-108764594-B Stability index system of water supply pipe network and evaluation method thereof 深圳市水务(集团)有限公司 2022-03-11 CN claimed
US-20200121271-A1 Medical Grid with Bar Codes DAVIS RANDALL PAUL (US) 2020-04-23 US claimed
US-10081588-B2 Production of butyl acetate from ethanol RESCURVE, LLC (US) 2018-09-25 US claimed
US-20160340588-A1 Halogen-Free Solid Flame Retardant Mixture And Use Thereof CLARIANT INTERNATIONAL LTD. (CH) 2016-11-24 US claimed
US-20160297737-A1 Production of Butyl Acetate from Ethanol VIRIDIS CHEMICAL, LLC 2016-10-13 US claimed
CN-105419396-A Carboxylated imidozoline phosphate activator for calcium carbonate LI ANPING 2016-03-23 CN claimed
EP-2958881-A1 PRODUCTION OF HIGHER ALCOHOLS Greenyug, LLC (US) 2015-12-30 EP claimed
WO-2015085002-A1 PRODUCTION OF BUTYL ACETATE FROM ETHANOL GREENYUG, LLC (US) 2015-06-11 WO claimed
EP-0987031-A1 Method for coating medical implants Isotis B.V. (NL) 2000-03-22 EP claimed
US-6000341-A Methods and composition for mineralizing and fluoridating calcified tissues AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1999-12-14 US claimed
EP-0825963-A1 BONE SUBSTITUTION MATERIAL AND A METHOD OF ITS MANUFACTURE ETEX CORPORATION (US) 1998-03-04 EP claimed
EP-0764014-A1 MOUTHRINSE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-03-26 EP claimed
WO-1996036562-A1 BONE SUBSTITUTION MATERIAL AND A METHOD OF ITS MANUFACTURE ETEX CORPORATION (US) 1996-11-21 WO claimed
WO-1995034276-A1 MOUTHRINSE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-12-21 WO claimed
US-5437857-A A deposited apatite is formed on teeth in situ after applying a mixed solution of amorphous calcium compound and a material forming amorphous calcium phosphate, calcium phosphate fluoride or calcium carbonate phosphate AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-08-01 US claimed
EP-0628017-A1 METHODS AND COMPOSITIONS FOR MINERALIZING AND FLUORIDATING CALCIFIED TISSUES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1994-12-14 EP claimed
WO-1994004460-A1 METHODS AND COMPOSITIONS FOR MINERALIZING AND FLUORIDATING CALCIFIED TISSUES AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1994-03-03 WO claimed
US-5268167-A Dental restorative; amorphous calcium phosphate fluoride and carrier AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-07 US claimed