Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623111 | 0.89 | ALDH1A1 (0.69) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL7410565 | 0.87 | PIM1 (0.66) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL11463231 | 0.87 | PIM1 (0.58) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL24138422 | 0.86 | PIM1 (0.51) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL17182493 | 0.86 | ALDH1A1 (0.56) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL6622094 | 0.82 | TP53 (0.60) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL12795524 | 0.82 | LMNA (0.51) | PIM1LMNATP53KDM4EGLA | |
| SCHEMBL5101629 | 0.82 | LMNA (0.51) | LMNATP53KDM4EGLAHPGD | |
| SCHEMBL8713204 | 0.81 | TPSAB1 (0.62) | PIM1PIM2 | |
| SCHEMBL13855906 | 0.79 | ALDH1A1 (0.63) | PIM1LMNAKDM4EGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450125-B | A kind of 5-replaces the synthetic method of benzofuran-2-carboxylic acid and derivative thereof | CHIMICA LABORATORIES CO., LTD. (CN) | 2016-01-13 | — | — | CN | disclosed |