Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514540 | 0.93 | LMNA (0.60) | NPC1RAB9ALMNATSHRTDP1 | |
| SCHEMBL513612 | 0.91 | TDP1 (0.61) | NPC1RAB9ALMNATDP1KMT2A | |
| SCHEMBL14287513 | 0.86 | LMNA (0.53) | NPC1RAB9ALMNATSHRTDP1 | |
| SCHEMBL11358478 | 0.86 | LMNA (0.53) | NPC1RAB9ALMNATSHRTDP1 | |
| SCHEMBL29104383 | 0.83 | TDP1 (0.66) | RAB9ALMNATSHRTDP1KMT2A | |
| SCHEMBL14898425 | 0.82 | ESR1 (0.52) | RAB9ALMNATSHRTDP1KMT2A | |
| SCHEMBL27914437 | 0.82 | KDM4E (0.60) | RAB9ALMNATSHRTDP1KMT2A | |
| SCHEMBL14722402 | 0.81 | NPC1 (0.72) | NPC1RAB9ALMNATSHRTDP1 | |
| SCHEMBL1688854 | 0.81 | TDP1 (0.61) | NPC1RAB9ALMNATDP1KMT2A | |
| SCHEMBL51601 | 0.80 | TDP1 (0.68) | NPC1RAB9ALMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103974928-B | Prepare the method for alkoxy aryl ester | SAUDI BASIC INDUSTRIES CORP. (SA) | 2015-12-23 | — | — | CN | disclosed |