SCHEMBL1688854

SCHEMBL1688854

Cc1ccc(C(=O)OCOC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.61
RAB9A P51151 4/20 0.59
ALDH1A1 P00352 4/20 0.59
NPC1 O15118 2/20 0.59
MAPT P10636 2/20 0.59
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
ESR1 P03372 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
ESR2 Q92731 1/20 0.55
CA14 Q9ULX7 1/20 0.55
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAOA P21397 1/20 0.53
ADRB2 P07550 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17896517 0.94 TDP1 (0.55) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL16627110 0.92 TDP1 (0.53) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL394866 0.90 TDP1 (0.52) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL513612 0.90 TDP1 (0.61) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL20127259 0.89 CA1 (0.58) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL513611 0.88 TDP1 (0.53) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL16785739 0.87 RAB9A (0.49) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL206554 0.86 TDP1 (0.61) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL235800 0.86 CA2 (0.73) TDP1RAB9AALDH1A1NPC1MAPT
SCHEMBL15592615 0.86 CA2 (0.56) TDP1RAB9AALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-10011772-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display device NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-07-03 US disclosed
US-9976086-B2 Liquid crystal aligning agent containing polyimide precursor having thermally-leaving group and/or polyimide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed
US-9864104-B2 Blend prepared by mixing a prepolymer and a vinyl monomer and a polymer sheet obtained therefrom ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2018-01-09 US disclosed
US-9732253-B2 Polyimide precursor, polyimide, and coating solution for under layer film for image formation NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-08-15 US disclosed
US-20160264867-A1 LIQUID CRYSTAL ALIGNING AGENT CONTAINING POLYIMIDE PRECURSOR HAVING THERMALLY-LEAVING GROUP AND/OR POLYIMIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2640728-B1 NOVEL MONENSIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF PROTOZOAL INFECTIONS MERIAL INC (US) 2016-09-07 EP disclosed
US-20160244673-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-08-25 US disclosed
US-9340691-B2 Hot melt ink composition comprising a copolyester and process for preparing a copolyester OCE-TECHNOLOGIES B.V. (NL) 2016-05-17 US disclosed
US-9303176-B2 Hot melt ink composition, method for preparing a hot melt ink composition and use of a hot melt ink composition OCE-TECHNOLOGIES B.V. (NL) 2016-04-05 US disclosed
US-20120128722-A1 Novel Monensin Derivatives for the Treatment and Prevention of Protozoal Infections MERIAL, INC. 2012-05-24 US disclosed
US-20120101236-A1 POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-26 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-12 US disclosed
US-20100172623-A1 COMPOUND CONTAINING CROSSLINKABLE MOIETIES, PREPOLYMER, BLEND AND POLYMER SHEET OBTAINED THEREFROM, AND WAVEGUIDE FOR OPTICAL INTERCONNECTION ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2010-07-08 US disclosed
US-20100069569-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND COATING SOLUTION FOR UNDER LAYER FILM FOR IMAGE FORMATION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-03-18 US disclosed
US-20100069569-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND COATING SOLUTION FOR UNDER LAYER FILM FOR IMAGE FORMATION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-03-18 US disclosed
US-20090184347-A1 COATING LIQUID FOR GATE INSULATING FILM, GATE INSULATING FILM AND ORGANIC TRANSISTOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-07-23 US disclosed
US-20090184347-A1 COATING LIQUID FOR GATE INSULATING FILM, GATE INSULATING FILM AND ORGANIC TRANSISTOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-07-23 US disclosed
EP-2028683-A1 COATING LIQUID FOR GATE INSULATING FILM, GATE INSULATING FILM AND ORGANIC TRANSISTOR Nissan Chemical Industries, Ltd. (JP) 2009-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100172623-A1 COMPOUND CONTAINING CROSSLINKABLE MOIETIES, PREPOLYMER, BLEND AND POLYMER SHEET OBTAINED THEREFROM, AND WAVEGUIDE FOR OPTICAL INTERCONNECTION CBS, CTH, WASF2 TDP1 4462/4885RAB9A 2877/4885ALDH1A1 2667/4885
US-20120088888-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND LIQUID CRYSTAL ALIGNING AGENT PUF60, F13A1, F12 TDP1 242/4885RAB9A 1123/4885ALDH1A1 4072/4885
US-20120128722-A1 Novel Monensin Derivatives for the Treatment and Prevention of Protozoal Infections MON2, SLC26A4, ABCB11 TDP1 4630/4885RAB9A 979/4885ALDH1A1 4624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.