Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | ATP4A | P20648 | 1/20 | 0.57 |
| ▸ | ATP4B | P51164 | 1/20 | 0.57 |
| ▸ | EIF4E | P06730 | 2/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048578 | 0.88 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL5997916 | 0.88 | ATP4A (0.63) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL12468446 | 0.85 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL30194268 | 0.83 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL9831049 | 0.82 | RAB9A (0.66) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12797778 | 0.82 | CYP19A1 (0.69) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL3956927 | 0.81 | ATP4A (0.55) | ALDH1A1NPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL27631751 | 0.81 | NR1H4 (0.54) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL14742925 | 0.79 | KMT2A (0.62) | ALDH1A1NPC1RAB9AHPGDHTT | |
| SCHEMBL167820 | 0.78 | RAB9A (0.58) | ALDH1A1NPC1RAB9AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103124729-B | As the pharmaceutical active compounds of Axl inhibitor | LEAD DISCOVERY CENTER GMBH (DE) | 2016-01-20 | — | — | CN | disclosed |