Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.53 |
| ▸ | CCND1 | P24385 | 3/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516136 | 0.92 | CCNB2 (0.49) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10373192 | 0.81 | DRD2 (0.54) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL31114357 | 0.78 | CDK4 (0.72) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL28154656 | 0.78 | HTR2C (0.41) | ALOX5DRD2DRD1DRD4DRD5 | |
| SCHEMBL3437970 | 0.74 | DRD2 (0.58) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL27516144 | 0.74 | ENPP2 (0.50) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL2918145 | 0.73 | HTR2C (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL14530044 | 0.73 | HTR2C (0.40) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL16951187 | 0.73 | TP53 (0.47) | ALDH1A1DRD2DRD1DRD4DRD5 | |
| SCHEMBL31519011 | 0.73 | TP53 (0.47) | ALDH1A1DRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254539-A | Para aminobenzoic acid derivatives and composition and application thereof | GUANGZHOU INSIGHTER BIOTECHNOLOGY CO LTD | 2016-01-20 | — | — | CN | disclosed |