Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918145 | 0.84 | HTR2C (0.43) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL24233712 | 0.81 | QDPR (0.55) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL28048626 | 0.78 | CCNB2 (0.53) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL15761724 | 0.78 | TSHR (0.45) | DRD2DRD3CYP3A4ATMCNR2 | |
| SCHEMBL15761705 | 0.78 | TSHR (0.45) | DRD2DRD3CYP3A4ATMCNR2 | |
| SCHEMBL28827508 | 0.77 | DRD2 (0.48) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL2922647 | 0.77 | DRD2 (0.48) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL677590 | 0.77 | HDAC4 (0.47) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL27516144 | 0.77 | ENPP2 (0.50) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL335941 | 0.76 | CNR2 (0.50) | CYP3A4ATMCNR2TYRNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254539-B | P-aminobenzoic acid derivative and combinations thereof and purposes | 广州英赛特生物技术有限公司 | 2017-06-06 | — | — | CN | disclosed |