Butanone

Butanone

SCHEMBL28048642

CC(=O)C(C)(C)C.CCC(C)=O

nearest known ligand 0.67

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
TDP1 Q9NUW8 3/20 0.67
FFAR3 O14843 1/20 0.39
TRPA1 O75762 1/20 0.37
GAA P10253 2/20 0.36
CES2 O00748 1/20 0.32
LMNA P02545 3/20 0.32
SLC15A2 Q16348 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
ADRA1A P35348 1/20 0.30
MGAM O43451 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butanol SCHEMBL23923797 0.83 ALDH1A1 (0.71) ALDH1A1TDP1FFAR3TRPA1GAA
Butanone SCHEMBL28350067 0.82
Butanone SCHEMBL1310 0.82
Butanone SCHEMBL1039820 0.82 ALDH1A1 (1.00) ALDH1A1TDP1FFAR3TRPA1GAA
Butanone SCHEMBL1510153 0.82
Butanone SCHEMBL8379087 0.82 ALDH1A1 (1.00) ALDH1A1TDP1FFAR3TRPA1GAA
SCHEMBL3229564 0.82
SCHEMBL43148 0.82
SCHEMBL3257772 0.82 LMNA (0.46) ALDH1A1TDP1FFAR3GAALMNA
Tert-Butanol SCHEMBL28779762 0.80 ALDH1A1 (0.67) ALDH1A1TDP1FFAR3TRPA1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102690268-B A kind of racemization method of eszopiclone CHENGDU HONGDA PHARMACEUTICAL CO., LTD. (CN) 2016-02-24 CN disclosed