Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167144 | 0.89 | ALDH1A1 (0.39) | ACHEALDH1A1TDP1MAPTCYP2C19 | |
| SCHEMBL28265212 | 0.85 | L3MBTL1 (0.57) | ALDH1A1TDP1L3MBTL1MAPTCYP3A4 | |
| SCHEMBL13926340 | 0.75 | ACHE (0.68) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL14160923 | 0.75 | ACHE (0.68) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL1457605 | 0.75 | ACHE (0.68) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL1144983 | 0.75 | MEN1 (0.45) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL10363196 | 0.75 | MEN1 (0.45) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL13507766 | 0.73 | ALDH1A1 (0.32) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL16166665 | 0.73 | ALDH1A1 (0.37) | ACHEALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL8563717 | 0.73 | ALDH1A1 (0.48) | ACHEALDH1A1TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189475-B | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | 动力欧勒德斯有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105189475-A | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LTD | 2015-12-23 | — | — | CN | disclosed |