Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 9/20 | 0.50 |
| ▸ | WNT3A | P56704 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969036 | 0.82 | PPARG (0.43) | CTNNB1WNT3ARAB9AL3MBTL1TSHR | |
| SCHEMBL29746616 | 0.79 | RAPGEF4 (0.48) | RAB9AL3MBTL1TSHRPPARGKDM4E | |
| SCHEMBL5069167 | 0.74 | TSHR (0.68) | RAB9AL3MBTL1TSHRPPARGKDM4E | |
| SCHEMBL27658377 | 0.73 | CYP11B1 (0.54) | RAB9AL3MBTL1TSHR | |
| SCHEMBL28169468 | 0.73 | OXER1 (0.40) | RAB9AL3MBTL1TSHRPPARGALDH1A1 | |
| SCHEMBL21462774 | 0.73 | PLA2G4A (0.41) | RAB9AL3MBTL1TSHRPPARGSMN1; SMN2 | |
| SCHEMBL18555462 | 0.73 | KDM4E (0.48) | RAB9ATSHRPPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL16496424 | 0.72 | ROCK2 (0.38) | RAB9AL3MBTL1TSHRPPARGSMN1; SMN2 | |
| SCHEMBL2473207 | 0.72 | ROCK2 (0.38) | RAB9AL3MBTL1TSHRPPARGSMN1; SMN2 | |
| SCHEMBL29453277 | 0.71 | TSHR (0.69) | RAB9AL3MBTL1TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188696-A | Gamma-diketones as WNT/beta -catenin signaling pathway activators | SAMUMED LLC | 2015-12-23 | — | — | CN | disclosed |