Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | PLAU | P00749 | 4/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 8/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782714 | 0.81 | ELANE (0.49) | ELANEF2PLAUBCHEACHE | |
| SCHEMBL27286651 | 0.76 | KDM4E (0.48) | — | |
| SCHEMBL5331216 | 0.76 | ELANE (0.43) | ELANEF2PLAURORC | |
| SCHEMBL27520009 | 0.73 | CNR1 (0.65) | ACHE | |
| SCHEMBL28048827 | 0.72 | MPO (0.40) | ELANEF2PLAU | |
| SCHEMBL27578607 | 0.71 | ELANE (0.45) | ELANEF2PLAURORC | |
| SCHEMBL4011064 | 0.71 | ELANE (0.45) | ELANEF2PLAURORC | |
| SCHEMBL27758519 | 0.71 | ELANE (0.57) | ELANEF2PLAURORC | |
| SCHEMBL9952327 | 0.71 | ELANE (0.45) | ELANEF2PLAURORC | |
| SCHEMBL1514915 | 0.71 | ELANE (0.60) | ELANEF2PLAURORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188696-A | Gamma-diketones as WNT/beta -catenin signaling pathway activators | SAMUMED LLC | 2015-12-23 | — | — | CN | disclosed |