Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 12/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273272 | 0.76 | ERN1 (0.38) | MEN1KMT2AERN1ELANE | |
| SCHEMBL28048850 | 0.72 | ELANE (0.40) | F2PLAUELANE | |
| SCHEMBL11752400 | 0.71 | LMNA (0.41) | MEN1HTTKMT2AELANE | |
| SCHEMBL27092032 | 0.65 | POLB (0.55) | ATMHTTKMT2AERN1 | |
| SCHEMBL5331216 | 0.62 | ELANE (0.43) | F2PLAUELANE | |
| SCHEMBL15968524 | 0.62 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL27745442 | 0.61 | ATM (0.44) | MPOATM | |
| SCHEMBL8682362 | 0.61 | KMT2A (0.43) | MPOMEN1HTTKMT2AF2 | |
| SCHEMBL7005408 | 0.60 | ALDH1A1 (0.38) | MEN1KMT2A | |
| SCHEMBL127188 | 0.60 | ELANE (0.43) | ATMKMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105188696-A | Gamma-diketones as WNT/beta -catenin signaling pathway activators | SAMUMED LLC | 2015-12-23 | — | — | CN | disclosed |