Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12493112 | 0.87 | OPRM1 (0.39) | AVPR1AKMT2ADPP7OPRM1SIGMAR1 | |
| SCHEMBL27655696 | 0.86 | NAMPT (0.43) | AVPR1AOPRM1CYP46A1SIGMAR1CYP2D6 | |
| SCHEMBL17978299 | 0.85 | DPP7 (0.41) | DPP7OPRM1SIGMAR1CYP2D6OPRD1 | |
| SCHEMBL27933676 | 0.83 | CYP46A1 (0.43) | KMT2AOPRM1CYP46A1SIGMAR1CYP2D6 | |
| SCHEMBL17700363 | 0.82 | ALDH1A1 (0.45) | OPRM1OPRD1OPRK1OPRL1HDAC3 | |
| SCHEMBL16101520 | 0.82 | OPRD1 (0.48) | OPRD1OPRK1 | |
| SCHEMBL3833018 | 0.80 | AVPR1A (0.62) | AVPR1AOPRM1CYP46A1OPRD1OPRK1 | |
| SCHEMBL12492896 | 0.79 | AVPR1A (0.37) | AVPR1AOPRM1CYP46A1SIGMAR1CYP2D6 | |
| SCHEMBL25663631 | 0.79 | OPRL1 (0.38) | OPRM1OPRD1OPRK1OPRL1HDAC3 | |
| SCHEMBL25663654 | 0.78 | SLC6A2 (0.39) | DPP7OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164119-B | 5-amino-quinoline-8-carboxamide derivatives as 5-HT4 receptor agonists | 苏文生命科学有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-105164119-A | 5-amino-quinoline-8-carboxamide derivatives as 5-ht4 receptor agonists | SUVEN LIFE SCIENCES LTD | 2015-12-16 | — | — | CN | disclosed |