Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438563 | 0.78 | ESR2 (0.45) | KEAP1TUBB1GAAPTGS2TUBB4A | |
| SCHEMBL8778284 | 0.77 | KEAP1 (0.42) | KEAP1TUBB1PTGS2TUBB4ATUBB | |
| SCHEMBL5133848 | 0.76 | KEAP1 (0.52) | KEAP1TUBB1GAAPTGS2TUBB4A | |
| SCHEMBL10829183 | 0.76 | CYP2A6 (0.48) | GAAKMT2APTGS1RAB9AMEN1 | |
| SCHEMBL1622032 | 0.74 | PGR (0.41) | GAAKMT2APTGS1RAB9AMEN1 | |
| SCHEMBL19351463 | 0.74 | KEAP1 (0.44) | KEAP1TUBB1GAAPTGS2TUBB4A | |
| SCHEMBL29093404 | 0.71 | PTGS1 (0.39) | GAAKMT2APTGS1RAB9AMEN1 | |
| SCHEMBL16049288 | 0.71 | PTGS1 (0.46) | GAAPTGS2KMT2APTGS1RAB9A | |
| SCHEMBL11629336 | 0.70 | RAB9A (0.49) | GAAKMT2APTGS1RAB9AMEN1 | |
| SCHEMBL26036242 | 0.69 | HSD17B10 (0.44) | TUBB1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |