Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD5 | P21918 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883324 | 0.89 | NOTUM (0.54) | DRD2DRD3NOTUMCASP3KDM4E | |
| SCHEMBL29564490 | 0.86 | NOTUM (0.52) | HTR7DRD2DRD5DRD3NOTUM | |
| SCHEMBL9828361 | 0.81 | NOTUM (0.46) | NOTUMCASP3KDM4EALDH1A1 | |
| SCHEMBL30404097 | 0.80 | HTR7 (0.54) | HTR7DRD2DRD5DRD3HTR1A | |
| SCHEMBL578249 | 0.80 | HTR7 (0.54) | HTR7DRD2DRD5DRD3HTR1A | |
| SCHEMBL7280026 | 0.78 | NPSR1 (0.62) | ALDH1A1 | |
| SCHEMBL6696116 | 0.78 | HTR7 (0.57) | HTR7DRD2DRD5DRD3NOTUM | |
| SCHEMBL8240109 | 0.78 | HTR7 (0.57) | HTR7DRD2DRD5DRD3NOTUM | |
| SCHEMBL7270605 | 0.77 | HSD17B10 (0.46) | NOTUMCASP3KDM4EALDH1A1 | |
| SCHEMBL27719562 | 0.76 | HTR7 (0.50) | HTR7DRD2DRD5DRD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150556-B2 | Benzimidazolone chymase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240702-A1 | Benzimidazolone Chymase Inhibitors | CMA1, SERPINB1, CPA3 | HTR7 2043/4885DRD2 4865/4885DRD5 4817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.