Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797988 | 0.82 | HTT (0.48) | P2RX7HDAC8HDAC6MAPK1ADRA1A | |
| SCHEMBL11408628 | 0.81 | HTT (0.47) | P2RX7MAPK1ADRA1ASMN1; SMN2TDP1 | |
| Acetic Acid SCHEMBL28825732 | 0.78 | HTT (0.45) | P2RX7MAPK1ADRA1ASMN1; SMN2TDP1 | |
| SCHEMBL8717921 | 0.74 | HDAC1 (0.50) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7393706 | 0.74 | P2RX7 (0.58) | P2RX7SMN1; SMN2TDP1POLBKMT2A | |
| SCHEMBL27595528 | 0.73 | HTT (0.43) | P2RX7MAPK1ADRA1ASMN1; SMN2TDP1 | |
| SCHEMBL162806 | 0.73 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL6371649 | 0.73 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL19452424 | 0.72 | HDAC1 (0.67) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL2222140 | 0.72 | HDAC1 (0.67) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687792-B | Prodrug of non-steroidal anti-inflammatory drug with rapid skin and biological membrane penetration speed and medical application thereof | YU CHONGXI (US) | 2016-03-02 | — | — | CN | disclosed |