Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.44 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408628 | 0.98 | HTT (0.47) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| Acetic Acid SCHEMBL28825732 | 0.95 | HTT (0.45) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL27595528 | 0.90 | HTT (0.43) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL28049411 | 0.82 | P2RX7 (0.52) | TDP1P2RX7MAPK1ADRA1ASMN1; SMN2 | |
| SCHEMBL11572663 | 0.80 | TTR (0.53) | MAPK1TTRAKR1B10UGT1A9TRPA1 | |
| SCHEMBL4414928 | 0.78 | ALDH1A1 (0.53) | MAPK1ALDH1A1L3MBTL1PAMSMN1; SMN2 | |
| SCHEMBL7759545 | 0.77 | HTT (0.45) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL2906104 | 0.75 | TSHR (0.49) | HTTTDP1P2RX7MAPK1ALDH1A1 | |
| SCHEMBL27937500 | 0.75 | EPHX2 (0.59) | P2RX7MAPK1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28214814 | 0.75 | KMT2A (0.50) | P2RX7ALDH1A1L3MBTL1TTRAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55045615-A | — | — | None | — | — | JP | disclosed |
| CN-108191846-A | High-penetration composition and its application | 于崇曦 | 2018-06-22 | — | — | CN | disclosed |
| CN-107929743-A | Treat the high penetrating power prodrugs composition and medical composition of pulmonary disease | 苏州泰飞尔医药有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107320732-A | High-penetration composition and its application | 于崇曦 | 2017-11-07 | — | — | CN | disclosed |
| CN-104173321-B | The method for preparing pharmaceutical composition being administered by external use plaster, with anti-inflammatory analgesic activity, and the composition obtained with this | 阿尔特根有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-107261149-A | High-penetration composition and its application | 于崇曦 | 2017-10-20 | — | — | CN | disclosed |
| CN-104974058-A | Positively-charged water-soluble diclofenac prodrugs with high skin penetration velocity | YU CHONGXI | 2015-10-14 | — | — | CN | disclosed |
| CN-1356981-A | Pharmaceutical compounds | NICOX SA (FR) | 2002-07-03 | — | — | CN | disclosed |
| EP-1159009-A2 | USE OF NIAOULI ESSENTIAL OIL AS TRANSDERMAL PERMEATION ENHANCER | FARMIGEA S.P.A. (IT) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000053228-A2 | USE OF NIAOULI ESSENTIAL OIL AS TRANSDERMAL PERMEATION ENHANCER | FARMIGEA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |
| US-4704468-A | Esters of O(2,6-dichlorophenylamino) phenylacetic acid | T P O "PHARMACHIM" (BG) | 1987-11-03 | — | — | US | disclosed |
| JP-S5545615-A | DERIVATIVE OF (N-ALLYL-O-(2,6-DICHLOROANILINO) PHENYL) ACETIC ACID | NISSAN CHEM IND LTD | 1980-03-31 | — | — | JP | disclosed |
| US-4189595-A | [N-benzyl-o-(2,6-dichloroanilino)phenyl]acetic acid derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |