Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059478 | 0.89 | CTSB (0.56) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL9059147 | 0.83 | ALDH1A1 (0.55) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL20509867 | 0.82 | CTSB (0.50) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL9059492 | 0.82 | ALDH1A1 (0.52) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL16054145 | 0.82 | MAPT (0.51) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL11398153 | 0.79 | HTT (0.54) | CTSBMAPTLMNAMAPK1ALDH1A1 | |
| SCHEMBL16166721 | 0.79 | KDM4E (0.61) | CTSBMAPTLMNAALDH1A1MITF | |
| SCHEMBL31022966 | 0.78 | ALDH1A1 (0.50) | CTSBMAPTTDP1ALDH1A1MITF | |
| Hydrochloric Acid SCHEMBL6046624 | 0.78 | ALDH1A1 (0.58) | CTSBMAPTLMNATDP1MAPK1 | |
| SCHEMBL23122845 | 0.77 | CTSB (0.49) | CTSBMAPTLMNATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283454-A | Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/MTOR pathways | ASANA BIOSCIENCES LLC | 2016-01-27 | — | — | CN | disclosed |