Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059478 | 0.90 | CTSB (0.56) | ALDH1A1TDP1CTSBMAPTKDM4E | |
| SCHEMBL3084638 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1CTSBMAPTL3MBTL1 | |
| SCHEMBL11398153 | 0.84 | HTT (0.54) | ALDH1A1CTSBSLC6A5MAPTL3MBTL1 | |
| SCHEMBL1199786 | 0.83 | MAPT (0.51) | ALDH1A1TDP1CTSBSLC6A5MAPT | |
| SCHEMBL28049531 | 0.83 | CTSB (0.50) | ALDH1A1TDP1CTSBMAPTKDM4E | |
| SCHEMBL9059492 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1CTSBMAPTKDM4E | |
| SCHEMBL20509867 | 0.83 | CTSB (0.50) | ALDH1A1TDP1CTSBMAPTKDM4E | |
| SCHEMBL16054145 | 0.83 | MAPT (0.51) | ALDH1A1TDP1CTSBMAPTMEN1 | |
| SCHEMBL31022966 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1CTSBMAPTL3MBTL1 | |
| SCHEMBL17565226 | 0.81 | MAPT (0.54) | ALDH1A1CTSBSLC6A5MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1368883-A | Method for lowering serum glucose and triglyceride levels and inhibiting angiogenesis using indolealkanoic acids | INST PHARMACEUTICAL DISCOVERY (US) | 2002-09-11 | — | — | CN | disclosed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |