Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577135 | 0.87 | F9 (0.49) | HTTMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL14103122 | 0.84 | PRKAB2 (0.48) | HTTLMNAMAPK1GRM2F9 | |
| SCHEMBL14102945 | 0.83 | GRM2 (0.47) | HTTMAPK1GRM2F9F10 | |
| SCHEMBL28048524 | 0.83 | MAPK1 (0.64) | HTTMEN1ALDH1A1KMT2AMAPK1 | |
| SCHEMBL8881389 | 0.82 | HTT (0.62) | HTTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL28011530 | 0.82 | MAPK1 (0.64) | LMNAMAPK1GRM2F9F10 | |
| SCHEMBL2567241 | 0.81 | MAPK1 (0.50) | HTTMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL28049587 | 0.81 | GRM5 (0.53) | HTTMEN1MAPTKMT2AMRGPRX4 | |
| SCHEMBL28244529 | 0.79 | ALOX5 (0.67) | MRGPRX4MAPK1F9F10MAOA | |
| SCHEMBL22517092 | 0.79 | MAPK1 (0.49) | HTTMEN1MAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263490-A | Substituted triazolopyridines and methods of use | GENENTECH INC | 2016-01-20 | — | — | CN | disclosed |