Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 13/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RORC | P51449 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643227 | 1.00 | PTGER4 (0.70) | PTGER4ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL15775066 | 0.83 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL15774961 | 0.81 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL5795412 | 0.80 | CYP1A2 (0.54) | PTGER4ALDH1A1KDM4ECNR2NPC1 | |
| SCHEMBL2734561 | 0.80 | ALDH1A1 (0.78) | PTGER4ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL13011130 | 0.79 | CNR2 (0.55) | PTGER4ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL16093881 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDKDM4ECNR2 | |
| SCHEMBL6529188 | 0.78 | TP53 (0.52) | PTGER4NPC1 | |
| SCHEMBL15774472 | 0.78 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL20631893 | 0.78 | RORC (0.77) | PTGER4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-105189488-A | Carbazole compounds useful as bromodomain inhibitors | BRISTOL MYERS SQUIBB CO | 2015-12-23 | — | — | CN | disclosed |