Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19179039 | 0.92 | CYP1A2 (0.50) | CYP1A2CYP2C19L3MBTL1DHFRPTGER4 | |
| SCHEMBL22441902 | 0.91 | PTGER4 (0.45) | CYP1A2CYP2C19L3MBTL1DHFRPTGER4 | |
| SCHEMBL7140681 | 0.90 | NPC1 (0.53) | CYP1A2CYP2C19L3MBTL1DHFRCNR2 | |
| SCHEMBL13471701 | 0.85 | PTGER4 (0.50) | L3MBTL1PTGER4CNR2RORCRORA | |
| SCHEMBL5795864 | 0.82 | RORC (0.51) | PTGER4CNR2RORCLMNAKDM4E | |
| SCHEMBL5797985 | 0.81 | PTGER4 (0.58) | PTGER4CNR2RORCKDM4ERORA | |
| SCHEMBL12216223 | 0.80 | DHFR (0.61) | DHFRCNR2RORCKDM4ERORA | |
| SCHEMBL29643227 | 0.80 | PTGER4 (0.70) | PTGER4CNR2RORCKDM4ENPC1 | |
| SCHEMBL4583419 | 0.79 | PTGER4 (0.41) | CYP1A2CYP2C19L3MBTL1DHFRPTGER4 | |
| SCHEMBL22441906 | 0.79 | PTGER4 (0.43) | CYP1A2CYP2C19L3MBTL1DHFRPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143005-A | Fluoro methyl bis-carbazolyl methane compound and synthesis method thereof | 宁波大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-109206360-A | Carbazole amide derivatives or its salt and its preparation method and application | 复旦大学 | 2019-01-15 | — | — | CN | disclosed |
| CN-104854098-B | Benzimidazole derivatives as EP4 antagonists | 拜耳医药股份公司 | 2018-01-09 | — | — | CN | disclosed |
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |