Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415336 | 0.84 | P2RX7 (0.45) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL5586737 | 0.80 | HPGD (0.50) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL990718 | 0.79 | GABRA1 (0.65) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL17471747 | 0.77 | CES2 (0.37) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL2885020 | 0.76 | P2RX7 (0.40) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL11859274 | 0.76 | P2RX7 (0.40) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL10799338 | 0.73 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL478223 | 0.73 | GABRA1 (0.62) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL30521988 | 0.73 | GABRA1 (0.62) | GABRA1GABRB2CA2CA1HPGD | |
| SCHEMBL15558016 | 0.72 | P2RX7 (0.35) | GABRA1GABRB2CA2CA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189438-A | Substituted aromatic compounds for treating fibrosis and related methods | PROMETIC BIOSCIENCES INC | 2015-12-23 | — | — | CN | disclosed |