SCHEMBL852646

SCHEMBL852646

COc1ccccc1CCO

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.64
SIGMAR1 Q99720 1/20 0.56
AOC3 Q16853 1/20 0.56
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
KCNH2 Q12809 1/20 0.55
IDO1 P14902 2/20 0.53
HRH3 Q9Y5N1 1/20 0.53
MPO P05164 2/20 0.53
CHRM2 P08172 1/20 0.52
CHRM1 P11229 1/20 0.52
ABCB1 P08183 1/20 0.51
ALDH1A1 P00352 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
LMNA P02545 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29474956 1.00 TAAR1 (0.64) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL2201042 0.96 TAAR1 (0.60) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
Lithium Ion SCHEMBL2201037 0.94 TAAR1 (0.58) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL11040584 0.89 CA12 (0.58) TAAR1SIGMAR1MTNR1AMTNR1BMPO
SCHEMBL28327254 0.88 TAAR1 (0.52) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL30118916 0.88 TAAR1 (0.60) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL80578 0.88 TAAR1 (0.60) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL28858018 0.86 TAAR1 (0.75) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL31277350 0.86 TAAR1 (0.58) TAAR1SIGMAR1AOC3MTNR1AMTNR1B
SCHEMBL7650103 0.86 TAAR1 (0.58) TAAR1SIGMAR1AOC3MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111630049-B Process for preparing 2- (5-methoxyisochroman-1-yl) -4, 5-dihydro-1H-imidazole and bisulphates thereof 奥赖恩公司 2023-06-20 CN claimed
CN-114653380-B Preparation method of spherical sludge-based solid acid catalyst, product and application thereof 淮阴师范学院 2022-11-15 CN claimed
CN-114653380-A Preparation method of spherical sludge-based solid acid catalyst, product and application thereof 淮阴师范学院 2022-06-24 CN claimed
US-11352346-B2 Process for the preparation of 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole and the hydrogensulfate salt thereof ORION CORPORATION (FI) 2022-06-07 US claimed
EP-3717476-A1 PROCESS FOR THE PREPARATION OF 2-(5-METHOXYISOCHROMAN-1 -YL)-4,5-DIHYDRO-1 H-IMIDAZOLE AND THE HYDROGENSULFATE SALT THEREOF Orion Corporation (FI) 2020-10-07 EP claimed
US-20200308152-A1 PROCESS FOR THE PREPARATION OF 2-(5-METHOXYISOCHROMAN-1 -YL)-4,5-DIHYDRO-1 H-IMIDAZOLE AND THE HYDROGENSULFATE SALT THEREOF ORION CORPORATION (FI) 2020-10-01 US claimed
CN-111630049-A Process for the preparation of 2- (5-methoxyisochroman-1-yl) -4, 5-dihydro-1H-imidazole and its bisulphate 奥赖恩公司 2020-09-04 CN claimed
US-9616459-B1 Polymeric coatings for fortification of visible, infrared, and laser optical devices LOCKHEED MARTIN CORPORATION (US) 2017-04-11 US claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
CN-101614971-B Photoresist cleaning agent ANJI MICROELECTRONICS CO LTD 2013-06-12 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-6613317-B1 In particular northern corn rootworm THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-09-02 US claimed
JP-2001507741-A 2001-06-12 JP claimed
EP-0951498-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME Althin Medical, Inc. (US) 1999-10-27 EP claimed
WO-1998029478-A1 MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME ALTHIN MEDICAL, INC. (US) 1998-07-09 WO claimed
US-5663265-A FREE RADICAL COPOLYMERIZATION FOR COATINGS HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-02 US claimed
US-5596057-A INTERPOLYMER FROM STERICALLY HINDERED UNSATURATED ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-21 US claimed
US-12577465-B2 Method for producing semiconductor treatment liquid and method for producing semiconductor element TOKUYAMA CORPORATION (JP) 2026-03-17 US disclosed
US-4123533-A Fused pyrimidine derivatives and compositions for treating atherosclerosis containing them CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308152-A1 PROCESS FOR THE PREPARATION OF 2-(5-METHOXYISOCHROMAN-1 -YL)-4,5-DIHYDRO-1 H-IMIDAZOLE AND THE HYDROGENSULFATE SALT THEREOF ADRA2A, ADRA2C, ADRB2 TAAR1 121/4885SIGMAR1 25/4885AOC3 2549/4885
US-11352346-B2 Process for the preparation of 2-(5-methoxyisochroman-1-yl)-4,5-dihydro-1H-imidazole and the hydrogensulfate salt thereof ADRA2A, ADRA2C, ADRB2 TAAR1 109/4885SIGMAR1 21/4885AOC3 2172/4885
US-12577465-B2 Method for producing semiconductor treatment liquid and method for producing semiconductor element PPA1, HAO2, SEM1 TAAR1 2395/4885SIGMAR1 2487/4885AOC3 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.