Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 4/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241353 | 0.77 | HCRTR1 (0.43) | SLC6A3HCAR2SLC6A2HTR1ASLC6A4 | |
| SCHEMBL648916 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2IKBKBHTT | |
| SCHEMBL30131336 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2IKBKBHTT | |
| SCHEMBL16212095 | 0.76 | P2RX7 (0.40) | SMN1; SMN2P2RX7MALT1CFD | |
| SCHEMBL16211769 | 0.76 | P2RX7 (0.40) | SMN1; SMN2P2RX7MALT1CFD | |
| SCHEMBL16211767 | 0.76 | P2RX7 (0.40) | SMN1; SMN2P2RX7MALT1CFD | |
| SCHEMBL32678883 | 0.75 | KDM4E (0.41) | P2RX7 | |
| SCHEMBL29661134 | 0.75 | KDM4E (0.38) | P2RX7 | |
| SCHEMBL2246378 | 0.74 | KDM4E (0.41) | P2RX7 | |
| SCHEMBL16394404 | 0.74 | HCRTR1 (0.44) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377036-A | Nematicidal N- (phenylcycloalkyl) carboxamides and N- (phenylcycloalkyl) thiocarboxamides | BAYER CROPSCIENCE AG | 2016-03-02 | — | — | CN | disclosed |